Purification and characterization of dihydrofolate reductase from Mycobacterium phlei.

نویسندگان

  • M Al-Rubeai
  • J W Dale
چکیده

The dihydrofolate reductase from Mycobacterium phlei was purified and characterized; it has an Mr of 15 000 and a pI of 4.8. It is competitively inhibited by both methotrexate and trimethoprim, although the affinity is less than for other bacterial dihydrofolate reductases.

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عنوان ژورنال:
  • The Biochemical journal

دوره 235 1  شماره 

صفحات  -

تاریخ انتشار 1986